An endometrial biopsy is a relatively quick and simple procedure. The endometrial biopsy can be performed right in your gynecologist’s office, although some cases may need to be done in the hospital. The difference between an endometrial biopsy vs. colposcopy is the removal of a tissue sample. There may be some bleeding after a uterine biopsy, which is why you may have to wait up to a week to have sex after endometrial biopsy procedures.

Endometrial Biopsy Procedure

During an endometrial biopsy, a small sample is taken from the lining of your uterus — the endometrium — so that it can be studied for signs of cellular abnormalities. You might also hear an endometrial biopsy referred to as a uterine biopsy. There could be several reasons why your doctor can recommend a biopsy:

An endometrial biopsy allows your doctor to examine the cells of your uterine lining under a microscope, and to see if anything looks abnormal. A biopsy can also allow your doctor to check for endometriosis, adenomyosis or endometrial cancer. It’s also a test to determine the effectiveness of hormone therapy. An endometrial biopsy is the only definitive way to diagnose uterine cancer, and the results are up to 95 percent accurate.

Endometrial Biopsy vs. Colposcopy

Unlike a colposcopy, an endometrial biopsy is used to help diagnose problems in your uterus. While both procedures can be helpful in determining the cause of unexplained or irregular vaginal bleeding, a colposcopy focuses solely on the cervix itself.


This is another difference in an endometrial biopsy vs. colposcopy: an endometrial biopsy removes cells from your uterine lining, not from your cervix. Depending on your symptoms, you may require both a colposcopy and an endometrial biopsy. Both procedures help your gyno in Queens diagnose gynecological issues, such as:

What to Do Before Your Endometrial Biopsy

Before your endometrial biopsy appointment in Rego Park or Forest Hills, New York, your gynecologist goes over the details of the procedure and answers any questions you have about the biopsy. You’re asked about any medications or supplements you’re taking, too, including vitamins and birth control pills. Make sure you give the doctor a complete and accurate medical history.

Sometimes, the doctor requests that you take an over-the-counter pain reliever before your appointment to minimize discomfort. When you arrive, you may be given a sedative to help you relax, but the procedure itself isn’t necessarily painful. You are given a hospital gown or drape to put on after you disrobe. The endometrial biopsy procedure can begin once you are resting on the examination table with your feet in stirrups.

During the Biopsy Procedure

Your gynecologist performs a pelvic exam and cleans your cervix and vagina before inserting a speculum. A clamp may be used to keep your cervix steady. You might feel some pressure or be a little uncomfortable. Tell your doctor if you do. Some patients report brief but significant pain or cramping when the cervical clamp is put in place.

Then, your gynecologist in Queens, NYC carefully guides a long, narrow tube through the opening in your cervix and into your uterus. He removes a small portion of the endometrium. The size of the sample depends on the reason for your endometrial biopsy. The entire procedure takes as little as 10 minutes, and you should be able to go home shortly after it is done.

What to Do After Your Endometrial Biopsy

It is a good idea to bring someone with you when you come for the procedure, especially if your doctor is using any form of anesthesia. Your doctor will go over specific recovery instructions after the procedure. Over-the-counter pain relief is usually sufficient to control post-endometrial biopsy cramping and pain.

You may experience some bleeding after uterine biopsy procedures, so it’s a good idea to wear a sanitary pad afterward. You should not use tampons or have sex for at least a week after the procedure. Be sure to follow your doctor’s instructions and keep any follow-up appointments. You will be contacted as soon as the results of your biopsy are received. You should contact your doctor’s office if you experience:

  • Severe bleeding
  • Bleeding that lasts longer than a couple of days
  • A foul-smelling discharge
  • Fever
  • Chills
  • Intense pain

Endometrial Biopsy Risks

The risks from the endometrial biopsy are minimal. As with any surgical procedure, however minimally invasive, there are some risks. Your risks include:

  • Infection
  • Prolonged or heavy bleeding
  • Puncture of the uterine wall, although this is extremely rare

If you are pregnant, an endometrial biopsy could lead to miscarriage, so it is important to let your doctor know if there is a chance you may be. It is recommended that you take a pregnancy test before the procedure just to be completely sure. If you have an infection or pelvic inflammatory disease (PID), these conditions may interfere with the biopsy. Your doctor will review the risks with you before you agree to the procedure.

Endometrial biopsy can help your doctor diagnose a variety of conditions. Early detection and treatment is essential, so if you have any unusual symptoms that worry you, do not delay a visit to your doctor.

Forest Hills Medical Services is a comprehensive clinical practice. In our office we believe that how you are treated is just as important as the medical care we provide. We are dedicated to providing the highest quality obstetrics and gynecology with warmth and compassion. Our physicians are easy to talk to and our entire staff is friendly and attentive to your needs.

The best gynecologists in Queens who are part of the Forest Hills Medical Services team are renowned for their extensive skills in performing endometrial biopsies and treating any condition the biopsy can help diagnose.

We will listen to all your concerns and together we will come up with the treatment plan that works for you and your unique circumstances.

Call FHMS to meet our staff in our state-of-the-art offices and be heard.

Gynecologists Dr. James Gohar (OBGYN Doctor), Dr Nithya Gopal and Maris Huffman, NP
Forest Hills Medical Services
108-16 63rd Rd
Forest Hills, NY 11375
1 (646) 472-5893